In view of the poor selfpropelled ability of the safflower picking mobile platform and the tilting of the position when working on uneven field ground, a safflower picking mobile platform was designed, and the overall performance of the mobile platform was analyzed theoretically to determine the rationality of the structural design of the mobile platform. The displacement and equivalent force of the mobile platform under bending and torsion conditions were simulated by ANSYS static analysis, the maximum deformation of the mobile platform was 2.95mm, which occured at the right rear wheel position of the mobile platform, the maximum stress was 235.8 MPa, which occurred at the rear wheel frame connection position, the overall displacement and strain was small, and the mobile platform structure met the requirements. The obstacle crossing and climbing performance test of the designed mobile platform was carried out, and the test results showed that the designed mobile platform could start smoothly and keep a certain speed to walk at a constant speed with good power performance, the ultimate overrun height was 61.2mm, the longitudinal ultimate tipping angle was equal to 19.7°, and the transverse ultimate tipping angle was 18.3°. The designed mobile platform has a good structure and performance, which can provide a comprehensive application platform for safflower picking machinery and can provide support for subsequent field trials.